Dr Nigel Francis

Research Highlights

1. Francis, N., Morgan, A., Holm, S., Davey, R., Bodger, O., & Dudley, E. (2020). Adopting a flipped classroom approach for teaching molar calculations to biochemistry and genetics students. Biochemistry and Molecular Biology Education, 48(3), 220-226.

   https://doi.org/10.1002/bmb.21328, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa53291
2. Vincent, E., Cronin, J., Panetti, S., Chambers, M., Holm, S., Owens, S., Francis, N., Finlay, D., Thornton, C., & Jones, N. (2019). Akt and STAT5 mediate naïve human CD4+ T-cell early metabolic response to TCR stimulation. Nature Communications, 10(1)

   https://doi.org/10.1038/s41467-019-10023-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa49646

   http://dx.doi.org/10.1038/s41467-019-10023-4
3. Jones, N., Cronin, J., Dolton, G., Panetti, S., Schauenburg, A., Galloway, S., Sewell, A., Cole, D., Thornton, C., & Francis, N. (2017). Metabolic Adaptation of Human CD4+ and CD8+ T-Cells to T-Cell Receptor-Mediated Stimulation. Frontiers in Immunology, 8(1516)

   https://doi.org/10.3389/fimmu.2017.01516, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36275
4. Jones, N., Piasecka, J., Bryant, A., Jones, R., Skibinski, D., Francis, N., Thornton, C., Skibinski, D., Jones, R., Thornton, C., Bryant, A., & Jones, N. (2015). Bioenergetic analysis of human peripheral blood mononuclear cells. Clinical & Experimental Immunology, 182(1), 69-80.

   https://doi.org/10.1111/cei.12662, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa23517
5. Francis, N., McNicholas, B., Awan, A., Waldron, M., Reddan, D., Sadlier, D., Kavanagh, D., Strain, L., Marchbank, K., Harris, C., Goodship, T., & Francis, N. (2011). A novel hybrid CFH/CFHR3 gene generated by a microhomology-mediated deletion in familial atypical hemolytic uremic syndrome. Blood, 119(2), 591-601.

   https://doi.org/10.1182/blood-2011-03-339903, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10484
6. Heurich, M., Martinez-Barricarte, R., Francis, N., Roberts, D., Rodriguez de Cordoba, S., Morgan, B., Harris, C., & Francis, N. (2011). Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk. Proceedings of the National Academy of Sciences, 108(21), 8761-8766.

   https://doi.org/10.1073/pnas.1019338108, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa44636
7. Heurich, M., Martinez-Barricarte, R., Francis, N., Roberts, D., Cordoba, S., Morgan, B., Harris, C., & Francis, N. (2011). Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk. Proceedings of the National Academy of Sciences, 108(21), 8761-8766.

   https://doi.org/10.1073/pnas.1019338108, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10487
8. Francis, N., Wong, S., Hampson, P., Wang, K., Young, S., Deigner, H., Salmon, M., Scheel-Toellner, D., & Lord, J. (2011). Lactoferrin inhibits neutrophil apoptosis via blockade of proximal apoptotic signaling events. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1813(10), 1822-1826.

   https://doi.org/10.1016/j.bbamcr.2011.07.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10485
9. Wong, S., Francis, N., Chahal, H., Raza, K., Salmon, M., Scheel-Toellner, D., Lord, J., & Francis, N. (2008). Lactoferrin is a survival factor for neutrophils in rheumatoid synovial fluid. Rheumatology, 48(1), 39-44.

   https://doi.org/10.1093/rheumatology/ken412, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa37318
10. Wong, S., Francis, N., Chahal, H., Raza, K., Salmon, M., Scheel-Toellner, D., Lord, J., & Francis, N. (2008). Lactoferrin is a survival factor for neutrophils in rheumatoid synovial fluid. Rheumatology, 48(1), 39-44.

    https://doi.org/10.1093/rheumatology/ken412, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10488
11. Wilkinson, T., Nibbs, R., & Francis, N. (2021). Reimagining laboratory‐based immunology education in the time of COVID‐19. Immunology, 163(4), 431-435.

    https://doi.org/10.1111/imm.13369, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57219

All Research

• Optimisation of T-cell metabolism for anti-cancer vaccination 2015 - 2016

  , with Professor Cathy Thornton, Dr Nick Jones, £30,000

• Targeted metabolic inhibition of T-lymphocytes induces differential cytokine production profiles 2016

  , with Professor Cathy Thornton, Dr Nick Jones, £50,000

• PhD Immunology, University of Birmingham

  October 2004 - July 2008

• Research Associate , Cardiff University

  October 2008 - September 2011

Pint of Science – Swansea 2018 and 2019 

• Becoming a Better Teacher – The Flipped Classroom

  February 2020

  University of Surrey

• The Future Graduate – The Importance of Group Wor

  January 2020

  Advance HE STEM 2020 Conference, Manchester

• Using online resources to engage students with laboratory-based teaching

  July 2019

  Advance HE Learning and Teaching Conference, Northumbria University

• eLearning revisited - engaging students with pre- and post- laboratory learning

  May 2019

  Cardiff University